Electronic media and education Essay

Electronic media is continuously expanding and is now to the degree where it has become a part of everyone’s life, not just in the Western world, it is starting to take hold worldwide.To define electronic media, it is a type of media that reserves and disperses electrical information through sources such as television, radio, and computers. Companies advertise to make consumers acquainted with the products or services provided and the only better way of performing this is through advertising on electronic media. Thus this essay will discuss the benefits and drawbacks of advertising through electronic media. To commence with, the major drawback of advertising through electronic media is that in the marketplace sometimes, electronic advertisement method convey a negative implication. Internet users typically find the ads unwelcomed to their online experience. Text ad and banners frequently are placed in the center of content, which obstructs the reader. The user cannot view the whole page as pop – ads appear over content, thus causing them to remove the ads. Audiences are so deluged with spam email and banner ads that they have begun to ignore electronic advertising just as much as ads on traditional media. Furthermore, advertising through electronic media has another stumbling block in its path. Electronic media is rather recent in comparison to print media and traditional broadcast but despite the ability to accumulate data and track users its prime technique for dispatching electronic advertisements remains evasive. To avoid pop-ups in the mid – the 1990s, these ads were disinclined. Currently, firms attempt to seize attention with richer media implements. A common example would be streaming audio and video advertisements. Financing money in media with insufficient years of knowledge and research is a challenge faced by them. Moreover, advertising through electronic media is high-priced and does not guarantee results. This advertising is acquired by an enterprise and stationed on the World Wide Web in key spots. For example, an electronic advertisement for air conditioning equipment may pop up alongside searches for air conditioning installation firms. For per click, it is paid in a click-through advertisement. Plus, the advertisement placing business sustains a levy when someone views the ad by clicking on it and the user is taken to the business website. People access these advertisements for free, even if they are not actually interested in buying the services or products. Clicking on these ads can be costly without a promise of a sale. Furthermore, viewers accessing a page with click-through advertisements click on the ads only 1 or 2 percent. Therefore, if just clicking on the ad is paid, it can result in a huge waste of money. On the other hand, there are also some benefits of advertising through electronic media. The Internet’s tremendous reach can enable promoters to contact altogether a larger number of individuals than traditional advertising media at a small amount of the cost. Electronic advertising is perfect for organizations with a national or worldwide target market and extensive scale appropriation capacities. When in doubt, the more individuals the business serves, the most cost-proficient electronic advertising can be. This can likewise be more focused than some customary media, guaranteeing that all the messages are seen by the most pertinent groups of audiences. As indicated by an article distributed in the New York Times, 96.7 percent of American families possess TVs. This adds up to more than 300 million individuals who approach the ads. Furthermore, advertising through electronic media offers the best creative opportunity among the traditional media. It has visual components like print and sound like radio, yet it likewise has dynamic development. Promoters frequently attempt to tell stories inside their advertisements that affect the group of audiences. Innovativeness can give more meaning intending to a brand past its basic product. For example, with TV, you can target passionate associations, consolidate characters that the audience can identify with and offer multi-tangible interest. To add on, advertising through electronic media empowers advertisers to be open for business all day and all night without stressing over store opening hours or additional time installments for staff. It has a benefit of 24/7 availability. Offering advertisements on the electronic media is likewise convenient for customers. They can browse the advertisement whenever makes them free to do.

Minority languages Essay

The world has very many languages that are considered as minor. These are well spread through the lands and they are threatened towards extinction. Various policies have been put forward by different countries to help preserve these unique dialects and one of the ways is by use of education scholarships given to people of these languages to encourage the to advance. As they advance, their languages get known in various places. Broadcasting stations that air programs in these languages have also been set up. Many more people can as a result hear them and adopt their ways. The culture of these minority groups can be used as a platform of preserving the dialects. Various campaigns have been set up to help market the culture of these people so that they remain dominant. Some countries have also gone to an extent of declaring that the minority languages are the national languages of their countries and this is a boost towards preserving the languages. Some education curriculums have also been set up so that these languages can be used in learning institutions and this has worked to spread awareness on these minority languages. This occurred in Sami which is an Irish dialect. Some important books like the bible have been printed in these languages and this gives security and helps to preserve the languages. The local owners of these languages are hence kept busy in their tradition and they feel comfortable and lack nothing because of the translations. The minor languages can best be preserved by making sure that the members fit in all arena of life by providing books and programs that are representative of their language. This is the only secure way. Source Tomasi, K. (2005). World History. NY: Oxford press.

Network managment Essay Example | Topics and Well Written Essays - 5000 words

Network managment - Essay Example r down; today performance management has become a crucial part of the IT teams role which brings about a host of challenges -- especially for global organizations. MAN: Metropolitan Area Network, a data network designed for a town or city. In terms of geographic breadth, MANs are larger than local-area networks (LANs), but smaller than wide-area networks (WANs). MANs are usually characterized by very high-speed connections using fiber optical cable or other digital media. A MAN is optimized for a larger geographical area than is a LAN, ranging from several blocks of buildings to entire cities. MANs can also depend on communications channels of moderate-to-high data rates. A MAN might be owned and operated by a single organization, but it usually will be used by many individuals and organizations. MANs might also be owned and operated as public utilities. They will often provide means for internetworking of local networks. Metropolitan area networks can span up to 50km, devices used are modem and wire/cable Some technologies used for this purpose are ATM, FDDI, and SMDS. These older technologies are in the process of being displaced by Ethernet-based MANs (e.g. Metro Ethernet) in most areas. MAN links between LANs have been built without cables using either microwave, radio, or infra-red laser links. DQDB, Distributed Queue Dual Bus, is the Metropolitan Area Network standard for data communication. It is specified in the IEEE 802.6 standard. Using DQDB, networks can be up to 30 miles long and operate at speeds of 34 to 155 Mbit/s. MAN adopted technologies from both LAN and WAN to serve its purpose. Some legacy technologies used for MAN are ATM, FDDI, DQDB and SMDS. These older technologies are in the process of being displaced by Gigabit Ethernet and 10 Gigabit Ethernet. At the physical level, MAN links between LANs have been built on fibre optical cables or using wireless technologies such as microwave or radio. The Asynchronous Transfer Mode (ATM) composes a

Compare and Contrast 2 Quality Management Theories Research Paper

Compare and Contrast 2 Quality Management Theories - Research Paper Example The basic contention behind the implementation of either Six Sigma or lean techniques is to increase the output from existing processes and methods. It must be taken to note that Six Sigma applies more to bolstering output by removing causes behind defects through the implementation of measurement and statistical techniques (Tennant, 2001). On the other hand, lean techniques consist largely of methods that are aimed at improving processes by looking at existing loopholes and reacting accordingly (Taylor, 2008). Need for Lean Techniques and Six Sigma in the Healthcare Sector Lean techniques are not based in large part on quantification unlike Six Sigma that dwells on quantifying defects for their removal and noting process improvement levels. In recent years, both Six Sigma and lean techniques have been used increasingly in the healthcare sector to deal with existing and emerging challenges. The increasing cost of healthcare and visits to doctors have meant that it is required to opti mize healthcare access costs through the application of Six Sigma and lean techniques. However, it must also be kept in mind that healthcare applications involve critical assessments that might end up with permanent damage to the patient’s health or might even result in a fatality (DelliFraine, Langabeer, & Nembhard, 2010). In such a case, the advantage of applying either Six Sigma or lean techniques is removed altogether as the customer is effectively permanently damaged or removed from the service list. On another note, it must be considered that the failure of Six Sigma or lean techniques in the manufacturing, services or other sectors may result in nothing more than another defect not involving loss to human beings. However, in the case of the healthcare industry, any failure of the Six Sigma or lean techniques regime could possibly lead to a human fatality which is not desirable. Therefore, the application of either Six Sigma or lean techniques requires differentiation b etween critical and non-critical applications in the healthcare sector. Requirements of Quality Management Philosophy in the Healthcare Sector The healthcare industry effectively requires a technique that is not harmful to the customers. In case that Six Sigma is applied to the healthcare industry, it would involve taking measurements as a vital method of producing baselines and quantifying output levels to see how processes have improved. As far as the manufacturing sector is concerned, Six Sigma is effective because the same manufacturing processes are being repeated to manufacture the end product. The continuous nature of the measurement ensures that Six Sigma can be applied across the board to the entire organization. Even if the services industry is considered, it becomes clear that similar end services are being provided to customers resulting in insightful measurements for Six Sigma improvements. However, the case of the healthcare sector is altogether different since any hea lthcare organization is servicing customers with multiple differentiated needs at the same time. For example, the same hospital could be dealing with emergency trauma patients as well as with cardiovascular disease patients. The wide range of processes required to satisfy the end customer do not favor Six Sigma for measurement in the healthcare sector (Taner & Sezen, 2007). Six Sigma In the case of the

Contract Law Exam seen case study Essay Example | Topics and Well Written Essays - 1000 words

Contract Law Exam seen case study - Essay Example In order to get that loan, he made Sophia sign on a deed which gave the Bank legal charge over her house. In this case, Tim has an undue influence over Sophia. He stands in a superior position to her and as, according to the given facts, Sophia is expecting her first child and wants to marry Tim, he can persuade her to do anything he wants. Also, Tim is described to be of an aggressive nature. It can be easily construed that Sophia gave the guarantee without knowing the consequences and she did that to secure her future with Tim as he had given assurances to her. He told her that he could afford to marry her only if he could raise some money and became a partner in the firm. That was the sole reason that Sophia agreed with Tim but she was not aware of the subtleties of this transaction. The only advice that she got in respect of this transaction was from Tim. Tim had undue influence over her and his advice would be disregarded. In Yerkey v Jones, a husband procured a guarantee from h er wife against his creditor. It was held that such a guarantee was not valid. In a special set of circumstances, such a guarantee is invalidated, they are: a. A husband procures his wife’s guarantee to obtain a loan; b. The guarantee is not for the benefit of wife but of husband; c. There is a default in repayment by the husband; d. The creditor relies on the wife to get repaid; e. The creditor does not have sufficient reasons to believe that the wife’s consent was free. Sophia’s consent was not free. Tim is not her husband but his relation with her and the facts of the case are quite similar those of Yerkey v Jones. The transaction was for the sole benefit of Tim and had nothing in it for Sophia. Tim has left Sophia after having an affair. The Bank seeks to get possession of her house. There are no sufficient grounds for Trusty Bank to believe that Sophia understood the transaction and gave a free consent. It was obtained under undue influence and resulted in a voidable contract. As Sophia is looking to get out of the contract, it can be easily construed that the contract would become void. Sophia’s guarantee would be invalidated and Trusty Bank would not be able to get possession of her house. Tim is still liable to pay the loan and Trusty Bank has all the rights of a creditor against Tim. Against Deluxe Kitchens Ltd In a legally binding contract, the parties involved must perform their respective promises according to terms on which they agreed on. If any of the parties does not perform its promise correctly, the other party becomes entitled to sue for damages. The damages involve the amounts of losses that are caused directly due to the negligence or fault of the other party. In the given case, Sophia had contracted with Deluxe Kitchens Ltd to build and install some new fitted kitchen units to match existing units and new kitchen equipment for ?15,000. The work was not done as it was promised and Deluxe Kitchens Ltd were 4 week s late in doing their job. Also, their work was not satisfactory. Sophia hired them to install units that would match her kitchen and they did not. Furthermore, there were some errors in their working. In order to fix those errors, almost ?3000 would be required. Sophia was without a cooker and she was offered by Deluxe Kitchens Ltd that they would install her old cooker but she refused. Due to delay in getting a new cooker, she was unable to cater for her sister’

World Wars I and II Research Paper Example | Topics and Well Written Essays - 2000 words

World Wars I and II - Research Paper Example In the Second World War, there was the Allies on one side and the Axis on the other side. Thus, there are a myriad of differences and similarities characterizing the two wars. This paper compares and contrasts the two wars with regards to their origins. The First World War began on July 28, 1914 and came to an end on November 11, 1918. The war was majorly fought in Europe and it incorporated the world’s greatest powers which had formed two major alliances opposing each other. On one hand, there was the Allies which was based on the Triple Entebbe of the United Kingdom, Russia and France (Dowswell, Brocklehurst, and Brook 57-59). On the other hand, there was the Central powers which consisted of the Tipple Alliance of Germany, Italy and Austria-Hungary. Even so, the alliances were not inclined to the six countries exclusively. With time, more and more nations joined the war expanding the alliances even further. Also, the alliances reorganized themselves as time went by. In the final analysis, there war attracted over 20 million soldiers across the world with Europeans constituting a larger percentage (Duffy). The origins of this war can be attributed to a myriad of both long-term and short-term causes in the world history. As such, the long-term factors include a variety of conflicts and hostilities that had marred the European nations prior to the war. This includes the imperialist foreign polices that had dominated the European great powers including the Russian empire, the French Republic, the Austro-Hungarian empire, the British Empire as well as the Italy. However, the most immediate cause of the war was the assassination of Archduke Franz Ferdinand, who was an heir to the Austria-Hungary throne. According to Duffy, the assassination occurred on June 28, 1914. Following this tragic assassination, a series of wars were triggered. To begin with, there was a Habsburg ultimatum against Serbia. Consequently, the alliances which had been

ANALYZING SPSS(PASW) SOFTWARE PART 2 Essay Example | Topics and Well Written Essays - 1250 words

ANALYZING SPSS(PASW) SOFTWARE PART 2 - Essay Example Lack of defined disposal mechanisms has led to environmental pollution that is the cause of today’s environmental degradation. The amount of money required to clean up the environments is such a burden since the number of players in the market have reduced market share of even the world largest information and Communication Company. To be able to maintain business value, the future for the players in the market remains in working on establishing sustainability through collaboration. Sustainable business value is thus achievable through established global environments that enhance economic development that are necessary for a global sustainable future. This thesis seeks to answer the following question: How can businesses leaders in the telecommunications industry shape the future of the telecommunications industry to arrive at a sustainable business value? Telecommunication industry has been one of the fastest growing industries in the globe (Goggin, 2014). The number of users has been on the rise by each passing day. In high population countries like India, 10 million people subscribe to telecommunication services each month (Prasad, Dixit, & Nee, 2010). Telecommunication has thus become an influential piece of technology that many people can no longer do without. Technology, has managed to bring people together to either work together or just use the services offered. However, with step in growth of the industry, the ecosystem gets the greatest effect. The methods of disposal of these gadgets have not been established for a long time. The e-waste that ends up in the landfills have proved to be more hazardous than any other waste ever know. Thus the needs for activities that focus on global network of companies have grown from a luxury to a necessity for survival of a player in the telecommunication industry as well as environmental conservation. Many key players have thus

Goal Setting Framework Term Paper Example | Topics and Well Written Essays - 500 words

Goal Setting Framework - Term Paper Example Due to the rising cost of distribution, Los Angeles Tribune will use any of the following strategies to achieve its set goal; distribute jointly with other producers to the consumers, use digital distribution channel, increase the number of middlemen companies to assist in distributing its products or create new subsidiaries in different cities and towns to reduce the distribution cost. Of all these strategies, the organization shall use digital distribution as one of the most appropriate strategies. Therefore, the organization will distribute most of its newspapers through online system. This tactic will ensure that customers subscribe for their newspapers for them to get access to the papers. Various activities need to be carried out in order to reduce the cost of distribution such as; proper education of the customers on how they will get the online papers without any constrain and advertising to the public to create awareness of the new move in the organization so that they are n ot surprised with the new organizations move (Barton, 2001). This is planned to reduce the cost of distribution by 10% in every month. This measure Barton of success will show the progress of the goal set to reduce the cost of distribution so that the profit realized may increase. The other goal is to increase circulation revenue. The Los Angeles Tribune is making strategies such as to increase the newspaper supply, increase the advertisement efforts or to reduce the prices to attract more customers. With the investigation, the organization has realized that the circulation revenue goes down due to an increase in the prices of its newspaper. Therefore, one of the tactics that the organization will use is to reduce the price of its papers so that it regains its market share in the next two months. This will be done through reducing other costs, which will result in a cut, in prices. As a measure of success, 5% price cut in

How persuasive are the design arguments Essay Example | Topics and Well Written Essays - 1000 words

How persuasive are the design arguments - Essay Example People always wanted to know much about the origin of humanity. This issue has always been mysterious for us and it really seems that nature that allowed us to touch upon its secrets, would like to hide the truth from humans. However, there are people, who dared to try to find out the truth. They are famous philosophers, who played an important role in the life of all of us. The philosophers devoted their lives to science in order to create the arguments, which attempt to explain the origin of humanity. The argument from design was widely discussed and serves as a foundation of the modern science. The given paper will make an overview of the arguments and come to corresponding conclusion. William Paley in his book Natural Theology (1802) paralleled between the living things intricacy and subordinate intricacy of a surveillance that was created by an intelligent creature, as it was known. This version is considered to be classic. Taking into account the reasoning from design, or teleological argument, the design that was discovered in the universe gave reason to talk about subsistence of the intelligent creator that is usually depicted as God. Paley underlined in his works that a watch could not become possible without the creator of this watch, thus it became clear that living creatures had no opportunity to exist without an intelligent creator. There is a version that living things are the offspring of intelligent design. It could be concluded that watches refer to the intelligent design, thus living creatures have similarity with them. The living things are â€Å"equipped† with the eyes, the main tools of gathering the information. Paley states: â€Å"[S]upp ose I found a watch upon the ground, and it should be inquired how the watch happened to be in that place, I should hardly think †¦ that, for anything I knew, the watch might have always been there. Yet why should not this answer serve for the watch as well as for [a] stone [that happened to be lying on the ground† (Paley, 1809. p.1). The idea of Paley is based generally on biological aspect and its intricacy. This version was seriously considered, when Mr. Darwin presented his famous evolution theory based on the natural selection in 1859. Darwin in this way explained how livings creatures, which are intelligent, could adapt in a perfect way to their environment, even if they were not so intelligent. By this statement Darwin doubted the Paley’s idea about the biological base of argument to design to a considerable degree. The 20th century gave birth to another argument that was connected to the cosmology. This argument is also called fine-tuning argument. It state s that it is possible to explain the life on the planet by the different independent natural processes, but the fact that the universe gave chance for the life existing on the privilege position, confirmed the presence of the intelligent creator. For example, you should understand that for life as it exists now at the earth many incipient conditions and values as well as physical constants are necessary. If these conditions do not operate in appropriate way or make some tiny error, life will be just impossible in our universe. This statement represents the additional proof of theory of the existence of some intelligent creature that made all conditions, values and constants work on life creation. Hurben and Drange claimed that the denomination of the different physical constants could be combined only with the possible found denomination. In this argument to design other possible combinations could not exist. In this case Carrier and Drange also claimed that such characteristic as f ine-tuning could be concerned as illusion, in the light of what was stated above. In the book called Dialogues Concerning Natural Religion by David Hume you can find critics to this theory. Norman Smith underlined that Hume’s criticism was not only pernicious but also complete. This point of

The Effects of Internet Addiction Essay Example for Free

The Effects of Internet Addiction Essay The Effects of Internet Addiction As we are living in a digital world, many people spend too much time using the Internet, and it is terrible to see more than 15 percent of people spend more than 11 hours a week using the Internet in different ways. However, do you want to have many health problems or social problems because of the Internet? As you know, being an introvert person, having sleeplessness, and getting sore eyes are the three common effects of Internet addiction. Being an introvert person is one way to affect your life negatively because of the Internet addiction. Many people believe that spending too much time in front of the monitor can separate them from other people, and make them feel introvert, shy, and unsocial person. In addition to that, if the parents spend a lot of time using the Internet, they children will learn to do the same. Consequently, the children will be addictive as same as their parents, and that is really so bad for children and adults too. Having insomnia is yet another reason of Internet addiction. Since people stay many times searching the websites, chatting with their friends, and doing many things online, so they will get used to sleep late every night, which is too bad for their health. For example, if we used to watch online movies at night, especially the horror movies, we would be scared and feel that we do not want to sleep, which is leading to insomnia. Getting eyes inflammation is one more reason of exaggeration to use the Internet. For instance, when you spend more than 11 hours a week looking at the computer screen, your family will tell you that your eyes become reddish. Due to the Internet addiction and its disadvantages at our eyes, most of ophthalmologists say that we have to reduce of exposure our eyes to computer screens. Furthermore, do you want to have ugly eyes because of the Internet? In conclusion, it is clearly noted that being introvert, having lack of sleep at night, and getting eyes problems are enough effects to stop addictive at the Internet, and use it in balance way for significant reasons only.

Internalization And Social Learning Theory Young People Essay

Internalization And Social Learning Theory Young People Essay According to research, the effects of inter-partner violence witnessed by the child or young person can cause significant internalized behaviours, whereby the emotional and psychological effects of the violence have caused common problems including anxiety,  [1]  social withdrawal  [2]  and depression  [3]  for children and young people. It is of our own ignorance that some people choose to presume that a child is just being quiet rather than experiencing significant stress and emotional problems (Calder 2004:57). It is this ignorance that increases the childs felt isolation alongside their psychological and emotional disturbances. It is arguable that the lack of mature coping strategies a child has, alongside the failure of others to recognise when a child needs help, is what puts them at greater risk of experiencing such traumatic and indeed clinical behaviours. For example, Davis and Carlson (1987)  [4]  found in their study regarding children of battered women that 68% of preschool children and 53% of school age children in their sample had depression that was of a clinical concern.  [5]   The internalised behaviours of depression, anxiety and social withdrawal are interestingly typical of what the abused mother (victim) often goes through (WHO 2000; Hester et al 2007; McCue 2008). According to the Home Office, 75% of domestic violence cases result in mental health consequences to women (Home Office, 2001). These behaviours are not surprising in relation the physical and emotional harm that domestic violence may cause. The victim may be fearful of when the man may next strike causing anxiety. Depression may come from thoughts and feelings that they cant get themselves and their children out of the abusive home. Furthermore, the stress, anxiety and depression caused by their situation may lead them to avoid social environments, withdrawing themselves from anything which may lead them to be noticed, questioned, embarrassed or shamed. One may question however, how do these behaviours in the child occur? When analysing the environment the child is subjected to, the reasons for why they may have symptoms of depression, anxiety and social withdrawal become apparent: Anxiety Constant reminders around their home may keep them anxious and fearful of when the violence may next occur; there may be broken furniture, blood stained carpets/walls as well as other reminders around the home, even cuts and bruises physically apparent on their parent, signifying the childs lack of control.  [6]   Withdrawal The child is silent and withdrawn. They will have learnt that silence and not being outspoken is the best way to behave if they dont want to get beaten or they do not want to see or hear their mothers beaten. This can be taught verbally and/or visually through associative learning means.  [7]  (Lieberman 2000:41-55). For example if they witness their father repeatedly violating their mother there are two responses; the mother stays quiet and does not respond-the consequence maybe that the father does not continue to be violent, the atmosphere may calm. The second response may consist of a volatile reaction from the mother, screams, shouts and/or crying-the consequence is that their father will continue to violate. Therefore the child learns and associates that being loud, outspoken and overtly emotional will increase the violence, so the child may become quiet and withdrawn with the hope that the violence will reduce. Depression The depression may stem from their insignificance, their silence, their feeling of powerlessness and the feelings of guilt for not protecting their mother. Feelings of powerlessness and guilt may increase the childs emotional and psychological trauma, particularly if there are no significant internal or external supports.  [8]   We can apply these behaviours to social learning theory, which is based on the principle that behaviours observed as a young person will become learned and modelled as if the behaviour they have observed is the norm.  [9]  For example if the normal social behaviours of an abused mother in the home involve depression, anxiety, quietness, such behaviours are likely to be modelled by the child, because of their attachment (psychological, emotional and biological) but also because they havent had the opportunity to learn any other behaviours. Social learning can also be applied by observing an actual activity and seeing what it achieves which is sometimes referred to as associative learning.  [10]  For example, children and young people who internalise their behaviours may do so because they have learnt from their parents relationship that when the mother is quiet and withdrawn the abuse is less likely to occur. A case study which demonstrates this kind of social learning behaviour has been highlighted by a case brought forward to the Domestic Violence Integrated Response Project (DVIRP), a support network based in the East Midlands (UK) which offers supports including the Break-Thru programme for children aged 7-16 years who have witnessed and or experienced domestic violence. An 8 year old boy was referred to the Break-Thru programme for therapeutic sessions after he had witnessed domestic violence. He saw his father hit his mother on a weekly basis. If he attempted to intervene his father would hit him too. Due to this the boy learned to stay upstairs where he would hear the abuse instead. This learning process is one which demonstrates the influence in staying quiet, withdrawing from difficult situations, as arguably this boy learnt that these internalized behaviours were the best way to act in order to reduce trouble. But what about those children who model and socially learn from the perpetrators behaviour? There has been significant research carried out surrounding the cycle of violence thesis and the social learning theory of aggressive behaviour  [11]  (Walker 1979; Straus 1990; Grusec 1992; Bandura 1997) because there is concern that children may learn from their parent, who is the perpetrator, that using such modes of behaviour is the only means of achieving what they want (Calder 2004:23). Effects on behaviour: Externalization and social learning theory A significant impact on children and young people who have witnessed domestic violence considers how the childs experience influences their externalized behaviours.  [12]  highlight how all but one study examining impacts of domestic violence found that children who were exposed to domestic violence on a regular basis externalised significant behavioural problems, most commonly: aggressive, hostile, disruptive and anti- social behaviours compared to children from non-violent homes, similar to that of the perpetrator (in this case the father). However one must consider that the significance of such externalised behavioural problems demonstrated in these cases will vary according to support mechanisms in place during and post domestic violence and other situational circumstances at the time of the study. For example some children and mothers were placed in refuges at the time of the studies  [13]  where a sudden change of home, school, friendships and adjustment to refuge livin g were most probable and likely to affect their behaviours differently to those who still live with the perpetrator. Historically scientists have questioned the motivation behind aggressive behaviour. Albert Bandura (1997)  [14]  , in particular, proposed a social learning theory that focuses on externalised aggressive behaviour and how it can be implanted by roots of observational learning. This theory considers that when children witness adults committing violent acts this will influence children to imitate or model this violent behaviour too.  [15]  Similar outcomes of observational learning have been found in other studies and research surrounding the effects of domestic violence upon behaviour. The case study regarding the 8year old boy brought forward by DVIRP, as discussed previously, highlighted that the boy displayed externalised behaviours including anger for which he had no outlet; this resulted in him copying his fathers behaviour and being aggressive by hitting his mum and breaking household possessions (Appendix 1). This case, along with other such cases which are demonstrated through research by the likes of McGee (2000)  [16]  and Abrahams (1994)  [17]  , highlight that childrens role models (parents) do heavily influence behaviours; if the child had not witnessed his fathers violent behaviour he may not have externalised aggression, he may have been able to diffuse his anger through alternative methods. Not only do such learnt externalised behaviours affect familial relationships, it has been suggested that children living in homes with heightened hostility are likely to resolve their own interpersonal difficulties, for example with peers, by imitating and utilizing the modes of aggression and hostility they have picked up from the home (Straus 1990)  [18]  , thus potentially leading them into drug and alcohol abuse, running away and juvenile delinquency.  [19]  Delinquency was shown in its extreme form by the media attention that surrounded the Sheffield Crown Court case on the Edlington attack where grievous bodily harm with intent was committed by two brothers aged 10 and 11. The barrister on the case implied that the two boys may have learnt such extreme violence and criminal behaviour from their parents. The barrister highlighted that the two boys had been subject to a toxic home life as they witnessed extreme domestic violence in the home; for example they saw their father threaten to slice their mothers face to bits with a knife (BBC News 21/1/2010).  [20]   On the contrary one must recognise that this case is an extreme form of externalization behaviour that has influenced a criminogenic life path, but there is no clear evidence to suggest the criminal acts carried out by the two boys were the sole consequences of learnt behaviour and such behaviours are not representative of all children who have been affected by witnessing domestic violence. However those who do exhibit hostile behaviours, whether it be on a low scale level or an extreme level are likely to affect important stages of their life, including the school learning process and involvement in peer socialisation; arguably two key aspects of developing the self during childhood.  [21]   Alongside the effects of externalised behaviours as a young person, researchers have also paid close attention to the impact of domestic violence on children and young people as they make transitions into adulthood. Many studies have found evidence for the intergenerational cycle of violence theory which argues that adults who externalize violent and abusive behaviour have most likely witnessed violent and abusive behaviour as children  [22]  23 Physical Symptoms Although children present in homes where domestic violence occurs are likely to suffer physical abuse as well, the physical effects of being the witness to domestic violence are quite different than symptoms of abuse, itself. The physical effects of domestic violence on children can start while the fetus is present in the mothers womb. Studies have shown that low infant birth weights are associated with both the direct physical trauma inflicted on the fetus mother, as well as the emotional stress that is placed on the victim of the domestic abuse. Direct physical abuse on the female victim can lead to multiple physical injuries associated with the infant child, ranging from premature birth, excessive bleeding, and even fetal death. Increased maternal stress during the times of abuse, especially when combined with smoking and drug abuse, can also lead to premature deliveries and low weight babies.[3] Infant children who are present in the home where domestic violence occurs often fall victim to being caught in the crossfire. They may suffer physical injuries from unintentional trauma as their parent is battered. Infants may be inconsolable and irritable, have a lack of responsiveness secondary to lacking t he emotional and physical attachment to their mother, suffer from developmental delays, and have excessive diarrhea from both trauma and stress. Physical effects of witnessing domestic violence in older children are less evident than behavioral and emotional effects. The trauma that children experience when they witness domestic violence in the home, plays a major role in their development and physical well being. The children, however, will exhibit physical symptoms associated with their behavioral or emotional problems, such as being withdrawn from those around them, becoming non-verbal, and exhibiting regressed behaviors such as being clingy and whiney. Anxiety like behavior is also a common physical symptom in children who witness domestic violence in the home. These children harbor feelings of guilt, blame, and are constantly o n edge. They may startle at the smallest things, such as a car door slamming or a glass cup accidentally falling to the floor. If their anxiety progresses to more physical symptoms, they may show signs of tiredness from lack of sleep and weight and nutritional changes from poor eating habits.[4] Children who witness domestic violence in the home can suffer a tremendous amount of physical symptoms along with their emotional and behavioral state of despair. These children may complain of general aches and pain, such as headaches and stomach aches. They may also have irritable and irregular bowel habits, cold sores, and they may have problems with bedwetting. These complaints have been associated with depressive disorders in children, a common emotional effect of domestic violence. Along with these general complaints of not feeling well, children who witness domestic violence may also appear nervous, as previously mentioned, and have short attention spans. These children display some of the same symptoms as children who have been diagnosed with attention deficit hyperactivity disorder. On the reverse, these children may show symptoms of fatigue and constant tiredness. They may fall asleep in school due to the lack of sleep at home. Much of their night may be spent listening to or witnessing violence within the home. Children of domestic violence victims are frequently ill, and suffer from poor personal hygiene. Children who witness domestic violence also have a tendency to partake in high risk play activities, self abuse, and death by suicide.[5] Children who witness domestic may show many physical symptoms of trauma, emotional stress, and possibly, physical abuse. Children who witness domestic violence in the home should be assessed for the physical effects of the violence by everyone around them. It is easy to see the physical injuries if the domestic violence turns into child abuse, however, the other physical findings may be difficult to evaluate. Any child who has changes in their eating habits, sleep patterns, or bowel patterns should be further examined or questioned by someone whom they trust. Behavioral Symptoms Domestic violence in the home affects children in different ways and the children exposed to this type of violence are likely to develop behavioral problems. Domestic violence can cause children to have regression with out of control behavior.[6] When a child is a witness of domestic violence, they often imitate behaviors. Children think that violence is an acceptable behavior of intimate relationships. They may develop a sense of social acceptance to this behavior and become the abused or the abuser. Some warning signs of domestic violence in children may be bed-wetting or having nightmares. Some children may become distrusting of adults. The child may try to act tough and have problems letting other people into their life and there are some children that may even isolate themselves from their close friends and family. Another behavioral response to domestic violence may be that the child may lie in order to avoid confrontation and excessive attention getting. Adolescents are in jeopardy of academic failure, school drop-out, and substance abuse. Their behavior is guarded and they are secretive about their family members. They get embarrassed ajbout the home situation. Adolescents dont like to invite friends over and they spend their free time away from home. Denial and aggression are their major forms of problem solving. Teens cope with domestic violence by blaming others, encountering violence in a relationship, or by running away from home.[7] An estimated 1/5 to 1/3 of teenagers who are involved in dating relationships are regularly abusing or being abused by their partners verbally, mentally, emotionally, sexually and/or physically. 30 to 50 percent of dating relationships can exhibit the same cycle of escalating violence in marital relationships.[8] Emotional Symptoms About 3.3 million children are exposed to domestic violence in their homes every year.[9] Not only are these children at risk for developing physical, behavioral, and social problems, but they are prone to develop emotional problems as well. These children often have conflicting feelings towards their parents. Feelings of distrust and affection often coexist for the abuser. The child becomes overprotective of the victim and feels sorry for them.[10] Children exposed to domestic violence often develop anxiety. They fear that they may be injured during an altercation between their parents, or even fear that their parents will abandon them. Children also worry about the safety of the parent that is being abused. Many times children fear that they are to blame for the violence that is occurring in their homes. Grief, shame, and low self esteem are common emotions that children exposed to domestic violence experience. Depression is a common problem in these children. The child often feels helpless and powerless. More girls internalize their emotions and show signs of depression than boys. Boys are more apt to act out with aggression and hostility.[11] Witnessing violence in the home can give the child the idea that nothing is safe in the world and that they are not worth being kept safe which contributes to their feelings of low self worth and depression.[12] Some children act out through anger and are more aggressive than other children. Even in situations that do not call for it, children will respond with anger.[13] Post Traumatic Stress Disorder can result in children from exposure to domestic violence. Symptoms of this are nightmares, insomnia, anxiety, increased alertness to the environment, having problems concentrating, and can lead to physical symptoms.[14] These children are not allowed a normal childhood. There is a role reversal between the child and the parent and the responsibilities of the victim who is emotionally and psychologically dysfunctional are transferred to the child. (see parentification.ua.edu)This is also known as parentification. 20,21 In this situation, the parents treat their child as a therapist or confidant, and not as their child. They are forced to mature faster than t he average child. They take on household responsibilities such as cooking, cleaning, and caring for younger children.[15] The responsibilities that they take on are beyond normal assigned chores, and are not age appropriate. The child becomes socially isolated and is not able to participate in activities that are normal for a child their age. The parentified child is at risk for becoming involved in rocky relationships because they have been isolated and are not experienced at forming successful relationships. Also they tend to become perfectionists because they are forced to live up to such high expectations for their parents.[16] Social Symptoms Children exposed to domestic violence frequently do not have the foundation of safety and security that is normally provided by the family. The children experience a desensitization to aggressive behavior, poor anger management and problem solving skills, and learn to engage in exploitative relationships.[17] The symptoms of children living with violence present differently at various ages of development. School age children exposed to domestic violence present with an excessive worry of possible danger and feelings of resentment towards the perpetrating party.[10] Symptoms include isolation from friends and relatives in an effort to stay close to siblings and victimized parent.[17] Adolescent children present with a difficulty in trusting adults and engage in excessive social involvement to avoid volatile situations at home. The adolescent may display these symptoms by joining a gang or becoming involved in dating relationships that mimic the learned behavior.[17] Children exposed to domestic violence require a safe nurturing environment and the space and respect to progress at their own pace. The caretaker should provide reassurance and an increase sense of security by providing explanations and comfort for the things that worry the children, i.e. loud noises.[10] The children should develop and maintain positive contact with significant others such as distant family members.[10] All family members are encouraged to become involved in community organizations designed to assist families in domestic violence situations. The behavioural effects of domestic violence on education and the school response 4.1 Overview Education is widely accepted as to boost economic and social capital as in to maintain ones life. It is widely understood accepted by the society that compulsory education is a must for children and young people. This is due to the system which emphasises on social skills (interacting with peers, tutors, involving in discussions), moral and cultural knowledge (through learning History, Music), organisation skills (cues in accordance, deadlines and school uniforms) and academic skills (through Maths and Science) which will be a leading path for them for a successful life path. The children who are not able to cope up with the education norms by truanting and excluding themselves will be a great concern for parents and teachers.  [24]   Domestic violence does not impose direct impact on children as per researches done, though the impacts are rather limited yet of great significance. However it has been proved relevantly that domestic violence does give negative impacts on children and young people in social settings which include school.  [25]   Pro social behaviour is seen in children and young people when the family setting is of positive  [26]  and negative result is seen in those of poor family attachment and negative family relationship between child and parents.  [27]   It is agreed that children and young people of domestic violence background are more likely to be involved in negative behaviours outside home which increase the probability of school difficulties. It is easy to say that the domestic violence impact affects the children and young people diversely when they do not conform with the education system and unable to achieve proper academic qualification. Those impacts include increased risk of later employment issues,  [28]  involvement in crime  [29]  and mental health problems.  [30]  It is not to discuss the current impacts of domestic violence After analysing the possible effects of witnessing domestic violence on the childs behaviour in the previous chapter, this chapter shall focus on analysing the effects that these negative internalised and externalised behaviours have on the childs education Internalised and externalised behaviours: Impact on schooling Learning As seen earlier those children who have been affected psychologically and emotionally by domestic violence have internalised behaviours of anxiety, social withdrawal and depression, and externalised behaviours of a disruptive and aggressive nature compared to normal life leading groups.  [31]   Mostly these type of affected children and young people are not able to control their behaviour from social settings outside their home where they will have problems in adult relationship, aggressive or poor communication with peers, low rate of concentration in school and overall poor achievements in school.  [32]   The aggressiveness which shown by these group of people is the outcome of the process of domestic violence at home. Ones these children are placed outside of their home frame, they are restless of what might b happening to their abused parent while they are not present at home. This situation increases the severity where they will ill treat those people around them in schools.  [33]   And if [Dad] beat Mum up I would be at school thinking.What if I go home and Mum isnt there? What if somethings happened? (Hannah aged 15 in McGee 2000:80). Internalised behaviours of fear and anxiety caused by home circumstances have been found to affect rate of concentration and involvement in school practices (Abrahams 1994). Children who have been traumatised and suffer from internalised behaviours are more likely to become totally withdrawn from their class; their state of mind becomes dissociated whereby they become completely disconnected from the environment they are in (the classroom), which results in them missing out on large amounts of information (Cole et al 2005:37). This withdrawal may significantly hinder their academic development and success, particularly because there is potential that educational support by some parents in an abusive relationship is likely to be weaker than in comparable relationships affecting home study. Externalised behaviours may also cause damage to the child or young persons learning process. According to Cole et al (2005:34) a traumatised child may exert aggressive or disruptive behaviours in the classroom to their teachers and peers. While other children in the class (and some teachers) may perceive this behaviour as troublesome and irrational, these externalised, aggressive behaviours maybe a result of Post-Traumatic Stress Disorder (Hester et al 2007) which can often be triggered by the actions, comments or tone of peers and teachers themselves. whenever I hear the teacher shouting, I just used to cover my ears cause I dont want to hear no one shoutingit was like bells ringing in my head (Karina aged 16 in McGee 2000:81). Some children who illicit aggressive behaviour towards a peer or teacher maybe doing so in frustration or defence because a particular tone, comment or action was expressed by them in the manner that the perpetrator did in the process of abuse they witnessed in the home. This illustrates how domestic violence can be detrimental to the communicative skills of children and young people because they gain distorted perceptions of the intentions, feelings, and behaviours of others (Rogosch and Cicchetti 1994 in Cole et al 2005:34) within the school environment. Social Exclusion and Impact on Attendance Not only are children likely to suffer academically because of their behavioural symptoms, their relationships with peers and other adults are also likely to be affected. Internalised behaviours such as depression, anxiety and withdrawal are symptoms which can exclude the www.internetjournalofcriminology.com Internet Journal of Criminology  © 2010 child or young person from their peers; their post-traumatic symptoms or behaviour may acutely disturb a developing close relationship with a best friend, create a sense of isolation from peers, or lead to social ostracism (Pynoos et al 1996:134). This social ostracism is further increased when children have to move schools because they need to be re-housed or take shelter in a womens refuge away from their violent home. This disconnection from both the academic and social life at school may lead children and young people who have been <

Dysfunctional Families in Revolutionary Road and Anna Karenina Essay

Dysfunction within an individual can be the result of various occurrences, whether it is a traumatic experience that has stemmed into a life of self-doubt and vulnerability, or it is a series of unfortunate events that has led the individual to believe that life is simply an ongoing controversy. However, dysfunction within a family is much more than self-afflicted stress, it is rooted within the familial bonds that gradually break as a result of conflict, co-dependent adults, perhaps substance abuse, and oftentimes a struggle of conformity brought on by an external source. In the novels Revolutionary Road and Anna Karenina, Richard Yates and Leo Tolstoy depict familial dysfunction that can occur as a result of society’s overwhelming ability to alter perspective and act as a catalyst to mediocrity. The characters that choose to conform to society’s moral values end up losing themselves in the process, causing dysfunction within the family unit; whereas the characters tha t choose to take their lives into their own hands and ignore society’s wrath ultimately prevail and restore moral order within themselves and within their families. Firstly, in Anna Karenina, the protagonist, Anna, is isolated by her hypocritical society with superficial values, which in turn leads her to her downfall. Secondly, in Revolutionary Road, John and April Wheeler are conflicted with society’s primary focus on materialism and wealth, which leads to the downfall of their dream causing their marriage to collapse. Similarly, both societies are led by the same motives where the protagonists of the novels seem to be corrupted by external sources, predominantly being their judgmental societies, which consequently causes the corruption of their families. Lastly, ... ...selves, and ultimately within the family unit by gaining a sense of perspective on what truly matters, being inner content, as opposed to societies judgment. The conflict of what truly causes a family to become dysfunctional wages on in literature, however Yates and Tolstoy inherently prove that the corruption of a family is typically the result of a degraded society with deteriorated morals. Bibliography †¢ Olesen, John, Joanne Fallon, and Louise Mark. Groups: a manual for chemical dependency and psychiatric treatment. Santa Fe, NM (342 Hillside Ave., Santa Fe 87501): CL Productions, 1993. Print. †¢ Tolstoj, Lev NikolaeviÄ . Anna Karenina. [Complete and unabridged]. ed. Ware (Hertfordshire): Wordsworth, 1995. Print. †¢ Yates, Richard. Revolutionary road. 3rd Vintage contemporaries ed. New York: Vintage Contemporaries, Vintage Books :, 2008. Print.

Balance and Tragedy in Shakespeares Othello Essay -- Feminism Literar

Mohandas K. Gandhi once proclaimed, â€Å"There is no occasion for women to consider themselves subordinate or inferior to men† (Gandhi n.p.). Women all throughout the world have been forced to endure innumerable hardships and struggles. Merely accepting women as a rightful component of society and a necessary aspect of culture has taken countless numbers of years. And to this day, unfortunately, gender equality has yet to become a reality for many. Certain judgments and stereotypes have been placed onto women from the very beginning of time. The belief that the female gender should only be seen in society as homemakers is something that is widely accepted by people in a multitude of countries and places. Despite the setbacks, various women have felt the need to fight for their rights and prove that they are an extremely crucial part of all societies. In the nineteenth century, the Cult of Domesticity, also known as the Cult of True Womanhood, was founded. It created s pecific rules that women in the United States and Great Britain were expected to follow. How well one obeyed the rules of the Cult of Domesticity dictated her reputation among fellow citizens (â€Å"From Domestic†¦Ã¢â‚¬  n.p.). The strict guidelines often had negative effects on individuals and prevented them from acting in an honest manner. In Othello, Shakespeare created the character of Emilia to perfectly represent the struggles women faced with fitting into their roles in society. The few female characters in the play were all shown in very different lights in order to demonstrate the varying types of women that could be seen in a normal society during that time. In William Shakespeare’s work Othello, Emilia’s imbalance of logic and emotion, a result of the pressur... ...ose to a balance, the chain reaction of events that led to the ultimate tragedy could not have been halted. If Emilia had come to her final realization earlier, could the tragedy have been stopped? Possibly, but it is impossible to know for sure. Even though it occurred, Emilia did, however, in the final moments of her life, speak with purpose and honesty. Her courage to stand up for her beliefs represents one of the most important themes in Othello and has made a truly lasting impact. Works Cited â€Å"From Domestic Goddesses to Suffragists: The Story of Women Told on Bookbindings, 1820-1920.† Publishers’ Bindings Online. U of Alabama, n.d. Web. 2 Nov. 2010. . Gandhi, Mohandas K. â€Å"Woman’s Status and Role in Society.† Mahatma Gandhi. N.p., n.d. Web. 2 Nov. 2010. .

Cigarettes - Addiction And Product Dangers :: essays research papers fc

It is clear that businesses have an obligation to inform their customers about their product's ingredients and dangers. Looking at the case of Rose Cipollone we see that she was a heavy smoker. Her doctor's had to remove part of her right cancerous lung and informed her that she had to quit smoking. Unfortunately, she was addicted. Her doctor's removed the rest of her lung that year and she finally quit smoking. She then sued the Liggett Group, the makers of the cigarettes she smoked. The lawsuit charged that the company knew of the link between cancer and smoking in the early 1940's. The company was found innocent of conspiring with other tobacco companies to hide the dangers of cigarette smoking but guilty on the grounds of falsely claiming its products were safe. However, things have changed. It is not 1940 anymore, when people were ignorant about the dangers of smoking. Tobacco companies now have Surgeon General warnings on cigarette packs. Unless they have been living under a rock, the general public should have been exposed to enough information by this time when it comes to cigarettes and addiction. Nicotine information is but a click away. Tobacco companies should no longer have the obligation to warn their customers, except if a new ingredient is added, in which case they should be notified. No one is saying get rid of the Surgeon General warnings, but enough is enough! If a person wants to smoke 3 packs of cigarettes a day, then that is their choice; tobacco companies should not be held responsible. Let us examine the hype surrounding the supposed danger and addition of nicotine. The Food and Drug Administration tells us that nicotine (the addictive drug found in cigarettes) is just as addictive as cocaine and should be illegal."Much of the rhetoric of the anti-smoking movement seeks to demonize tobacco smokers as "nicotine addicts". In the past, of course, the term "addict" has been generally applied only to mind-altering drugs, e.g., heroin and cocaine. Even alcohol, which is mind-altering, is not generally referred to as "additive". So, the argument is one of semantics. If nicotine is addictive, so are chocolate candies, pies and cakes, etc. Indeed, if "addiction" is defined as dependence upon some chemical, everyone is addicted, to air!" Nicotine and cocaine are two different things. They may be just as addictive as each other but they certainly do not produce the same effect.

Integration of faith no name

The Merriam Webster cautionary defines character as, â€Å"the good qualities of a person that usually include moral or emotional strength, honesty, and fairness†. From the beginning of time, people have had the example of negative and positive character. The lesson comes from the Bible in Hebrews 13:18 Pray for us: for we trust we have a good conscience, in all things willing to live honestly. These qualities, as stated in Hebrews make a successful leader. A successful leader has a victorious team which will produce quality products and attract loyal customers.Kettle and Keller state the vital role for any COM is to instill a customer viewpoint and create a loyal clientele (Kettle & Keller 2012). This is done through marketing and includes everyone in the company to reach to consumers. Within the marketing management the holistic marketing approach of 4 elements carries the workload that all employees should know the needs, wants, and interests of their market. This leads to value and satisfaction. If corners are cut to make a cheaper product the customer will not be happy with the quality.Building or providing high quality goods and services are a sign of character, being honest with good conscience. What would the employee or company do when no one is looking? Would they do the right thing and be honest? Or would they lie, cheat, and steal to close a deal with a customer or client? The best companies will be the ones that give back to the community and help those in need that may be down on their luck. A well known restaurant chain of having a good honest character is Chick-fill-a.As of last year 2014, Chick-fill-a has given over $68 million to education and various charities, working closely with the community. They have successfully built a loyal market. They also value family time and allow their employees a day off, Sunday. By being an example of giving to the community and creating a firm foundation in character, people are attracted to the value s and passion of this restaurant. A mission statement, ‘this is where you breathe real life into the lungs of your organization† (Ramsey 201 1).

Medal of Honor

When President Ronald Reagan presented Roy Perez Benavidez with his Medal of Honor in 1981, the President told the media that if someone had written a fictional story with a hero like Benavidez, nobody would have believed it. And, in fact, in his autobiography Medal of Honor: One Man’s Journey from Poverty and Prejudice, the story Benavidez tells is the stuff that movies are made of. Benavidez was an orphan in south Texas, a half-breed Indian and Hispanic in an era when neither was acceptable.He dropped out of school before even making it to high school, but as a staff sergeant in the Army during the conflict in Vietnam; he saved eight other men and prevented classified documents from falling into the hands of the enemy. (â€Å"Vietnam War Medal of Honor Recipient†) In essence, Benavidez is a true American success story. He was born to migrant farm workers and received the highest commendation that the United States offers for bravery in conflict. However, it may have b een Benavidez never say die attitude that did more to establish his positive contributions to American society than his war record.As the medevac chopper landed the wounded were examined one by one. Staff Sergeant Benavidez could only hear what was going on around him. He had over thirty seven puncture wounds. His intestines were exposed. He could not see as his eyes were caked in blood and unable to open. Neither could he speak, his jaw broken, clubbed by a North Vietnamese rifle. But he knew what was happening, and it was the scariest moment of his life, even more so than the earlier events of the day. He lay in a body bag, bathed in his own blood. Jerry Cottingham, a friend screamed â€Å"That's Benavidez. Get a doc†.When the doctor arrived he placed his hand on Roy's chest to feel for a heartbeat. He pronounced him dead. The physician shook his head. â€Å"There's nothing I can do for him. † As the doctor bent over to zip up the body bag. Benavidez did the only thi ng he could think of to let the doctor know that he was alive. He spit in the doctor's face. The surprised doctor reversed Roy's condition from dead to â€Å"He won't make it, but we'll try†. (Rouse) These were the wounds that Benavidez received the day he save eight men and won a Medal of Honor, but the reality is this was not the first time he had been gravely wounded in Vietnam.Four years earlier, in 1964, Benavidez was hit with shrapnel from a land mind and doctors said he would not recover. They said he would never walk again. They were wrong. In an exerpt from his book, Benavidez explains, Night after night, I bailed out of bed, crawled for the wall at the head of my bed and pulled myself up. I pushed the nightstands ahead with my arms, pressed my feet against the cold tile floor, and dragged my dead body along until my arms were under me again. Then I'd start all over again. Finally, I was moving about two tiles at a time. . .I had learned that if I got knocked down, I had to get up and keep fighting until I knocked my opponent down, and he didn't get up. Every night I got knocked down. Every night I got back up again. . . The pain was like nothing I could have ever dreamed about. Every night it would suck the sweat and tears from my body and my soul. Every day I would go back to that little chapel and sit alone and restore my soul. I went through all the stages of blaming God, accusing, doubting, and arguing, but he never deserted me. He'd never let me leave that chapel until I was ready to try again.After chapel, I went to physical therapy to try to restore the rest of my body for my nightly battle. In therapy I'd sit with the guys with no legs, or the true paraplegics, and learn how to live in the chair. I was not a good student. I wouldn't give in to the chair. At night I was beginning to win my battle, and I wasn't going to let the therapists convince me that it was a lost cause. (â€Å"Vietnam Medal of Honor†) That strength of spirit is perhaps the most lasting contribution Benavidez made to his country. Years later, as he lay dying, Benavidez had the same attitude.With two pieces of shrapnel still in his heart and a collapsed lung and diabetes, he reportedly said â€Å"quitters never win and winners never quit,† in his last interview, saying that he wanted to recover so he could continue working as a motivational speaker. (Mishalov) Another of Benavidez’s lasting contributions to the country came in the form of his activism after winning the Medal of Honor. During the Reagan Administration, Social Security attempted to cut his disability benefits, saying that the disabled war hero should find work.Though he regretted using his Medal for political purposes, he wore it as he testified to a Congressional committee regarding the unfairness of their Social Security budget cuts (Mishalov). Benavidez’s contribution are numerous, based mostly around his attitude of try, try again. He has an elemen tary school named for him and the U. S. Navy named a ship in his honor, a rare occurrence for the Navy to honor a member of another branch of the service. But Benavidez set all the honors and praise aside, saying that he did not consider himself a hero for his actions the day he won the Medal of Honor.The heroes, he said, were the men who lost their lives for their country. His actions were simply â€Å"his duty. † (Mishalov). Benavidez died of diabetes-related complications in November, 1998. Works Cited Mishalov, Neil. â€Å"Medal of Honor: Roy P. Benavidez† June 14, 2007. Rouse, Ed. â€Å"Roy P. Benavidez† , June 14, 2007. â€Å"Vietnam War Medal of Honor Recipient† http://www. medalofhonor. com/RoyBenavidez. htm>, June 14, 2007.

Crime in Literature

When crime features in literature, there are often many ways it is dealt with. In â€Å"Thank You Ma’am† by Langston Hughes, Mrs. Jones was almost robbed by a boy named Roger. Instead of calling the cops Mrs. Jones took the boy home to her house, washed, fed and gave him money to buy the sneakers that he had wanted to steal the money for. In contrast, in Roald Dahl’s â€Å"Lambs to the Slaughter†, Mary kills her husband, Patrick Maloney, after he told her he is going to leave her. After killing her husband, she tricks the police that she found him dead when she came home and also tricked them into eating the leg of lamb that she killed him with.While the lesson that is taught in each literature work are far different from each other, both show that crime is treated differently in many cases. However, were as Hughes illustrates the lesson that is being taught about theft, dhal demonstrates the unexpected turn in a common crime. In both works of literature w orks, â€Å"Thank You Ma’am† and â€Å"Lambs to the Slaughter†, crime is a common theme. Though in both literature works crime is conveyed differently. In â€Å"Thank You Ma’am† Mrs. Jones is almost robbed by a young boy Roger. But instead of calling the cops, Mrs.Jones catches him and takes him home where she taught him that stealing may not be the solution to his problems. In contrast, in â€Å"Lambs to the Slaughter†, Mary Maloney kills her husband, Patrick Maloney. But instead of getting caught, she finds a way to cover her tracks. Though both themes were crime, it’s shown in different ways. In â€Å"Thank You Ma’am† the theme can portrayed as crime is solved by forgiveness. Mrs. Jones shows roger forgiveness which made the reader believe that roger will change his ways. In â€Å"Lambs to the Slaughter† the theme shows that crime can be solved by lying.Mary will not go to jail because she covered her tracks an d the cops can’t trace her to her husband’s murder. Another example of how the theme is different by the ending of each story. In the end of â€Å"Thank You Ma’am† roger leaves Mrs. Jones house changed, speechless of what just happened to him. However, in â€Å"Lambs to the Slaughter† Mary giggles at the end of the story. This can show that both works of literature were conveyed differently throughout each story. Therefore, this shows how he crime is common in both works of literature through to theme is different. These two examples show how the themes are different.In both works of literature, â€Å"Tank You Ma’am† and â€Å"Lambs to the Slaughter†, characterization is a common influence on how each story plays out. However in each works of literature characters influence in different ways. In â€Å"Thank You Ma’am† Mrs. Jones helps roger realize what his wrong doing was. Therefore, Mrs. Jones influences roger t o realize what he has been doing wrong. In contrast, in â€Å"Lambs to the Slaughter† Mary tricks to police into eating the lamb, the weapon in Patrick murder case. This shows that Mary influence the police to believe that she did not kill her husband.In â€Å"Thank You Ma’am† Mrs. Jones could be characterized as kind. It was kindness that Mrs. Jones showed Roger for him to realize his wrong doings. And yet, in â€Å"Lambs to the Slaughter† Mary can be characterized as manipulative. In addition, the characterization could change the seriousness of a crime. In â€Å"Thank You Ma’am† Roger is characterized as a minor. He was just a young boy who had potential of changing his ways. In â€Å"Lambs to the Slaughter† marry could be characterized, in this case, as a consequential adult. Mary was dealing with a serious crime that she had committed.This shows that even though both works of literature consist of crime, the authors illustrates a different kind of crime in each by using the characterization of each character. Roger was a kid with a chance of change, who as just committed a robbery, but in Mary’s case she as an adult that had committed a murder. Through characterization, these stories consist of a common trait, but are conveyed differently. These two examples show how the two text are different. In conclusion, throughout both works of literature, there were common traits that consist in the story that is told by convey themselves differently.In both â€Å"Thank You Ma’am† and â€Å"Lambs to the Slaughter† consist of crime, but in each work they convey itself differently than the others. † In â€Å"Thank You Ma’am† crime was resolved by forgiveness. In â€Å"Lambs to the Slaughter† crime was solved by lying. Both works also consist of characterization that play out the story, but is used differently in each one. In â€Å"Thank You Ma’am† Mrs . Jones characterization help roger for the better. In â€Å"Lambs to the Slaughter† Mary’s characterization helped her for the bad. There were common trait but all was conveyed differently to create a different reaction of each literature works.

Discovered Biological Functions Of Rna Health And Social Care Essay

Recently, the figure of ascertained biological maps of RNA has been increasing. In add-on, the range has been expanded, and therefore RNA is non merely a inactive courier of familial information from Deoxyribonucleic acid to proteins makers as had been thought earlier. It has been found that RNA plays of import functions in all of molecular biological science such as transporting familial information ( messenger RNA ) , construing the codification ( ribosomal RNA ) , and reassigning familial codification ( transfer RNA ) . It besides performs different maps which include: catalyzing chemical reactions [ 1 ] , [ 2 ] , directing the site specific alteration of RNA bases, commanding cistron look, modulating protein look and helping in protein localisation [ 3 ] , [ 4 ] . The map of RNA molecules determine many diseases caused by RNA viruses. Identifying the secondary construction of RNA molecules is the cardinal key to understand its biological map [ 5 ] . The RNA construction anticipation methods, is tremendously affected by the quality of alignment [ 6 ] . MSA significantly improves the de novo anticipation truth of proteins or RNAs structures [ 7 ] . For illustration, current RNA secondary construction anticipation methods utilizing aligned sequences is win in deriving higher anticipation truth than those utilizing individual sequence [ 8 ] . Multiple sequence alliance ( MSA ) has become widely used in many different countries in bioinformatics. Multiple alliances are present in most of the computational method used in molecular development to assist happening sequences household, predict the secondary or third construction of new sequences, RNA folding, cistron ordinance and polymerase concatenation reaction primer design [ 9 ] , foretelling maps, predict patient ‘s diseases by comparing DNAs of patients in disease find. MSA is the most natural manner to see the relation between sequences by doing an alliance between the primary sequences so that indistinguishable or similar residues will be aligned in columns. That is why this method is so called multiple sequence alliance ( MSA ) . At kernel, all widely MSA tools used to better the alignment quality of initial alliance [ 10 ] . The sequence alliance job can be considered as an optimisation job in which the aim is to maximise a marking map [ 11 ] . One chief challenge with MSA is how to gauge the quality of computer-aligned sequences. An nonsubjective map ( OF ) is required in the optimisation processes to happen the optimum alliance. The pick of nonsubjective map is critically of import in obtaining high quality alliances [ 12 ] . In add-on, OF acts an indispensable function in optimisation algorithms whereby there is a relation between the alliance mark with the mark computed by the alignment quality. MSA optimisation job is NP-complete [ 13-15 ] , which motivates, the research for heuristics [ 16 ] . Over the last decennary, the evolutionary and meta-heuristic are the recent attacks to work out the optimisation job. Consequently, most of practical MSA algorithms are based on heuristics to obtain moderately accurate MSA within moderate computational clip and normally produce quasi-optimal alliance. Many researches solve MSA job as optimisation job by utilizing familial algorithm [ 17, 18 ] , Particle Swarm [ 11 ] , ant settlement [ 19 ] , and Simulated tempering [ 20 ] . MSA job can be resolve as optimisation job based on harmoniousness hunt algorithm [ 21 ] to maximise the nonsubjective map and happen the optimum alliance. The purpose of this paper is to analyze and examined the correlativity of different nonsubjective maps utilizing standard sets of RNA datasets. The most straightforward OF is the sum-of-pairs ( SP ) score [ 3 ] , weight sum-of-pair [ ] , java [ 22 ] , Xstate [ ] and NorMD [ 23 ] . This paper is organized as follows: Section 2 introduce the multiple sequence alliance job. Section 3 explains the different nonsubjective map from the state-of-the-art. Section 4 explains the proposed methodological analysis. The rating and analysis methodological analysis that is used to measure our comparing is explained in Section 5. Last, Section 6 provides the decision and sum-up of the paper.2.0 Multiple Sequence AllianceA sequence is an ordered list of symbols from a set of alphabet S ( 20 amino acids for protein and 4 bases for RNA/DNA ) . In bioinformatics, a RNA sequence is written as s = AUUUCUGUAA. It is a twine over the set S of bases symbols Adenine ( A ) , Cytosine ( C ) , Guanine ( G ) and Uracil ( U ) : S = [ A, C, G, U ] . Alignment is a method to set up the sequences one over the other in a manner to demo the matching and mismatching between residues. A column, which has lucifer residues, shows no mutant is go oning. Whereas, the column with mismatch symbols shows that several mutant events are go oning. To better the alliance mark, the character â€Å" – † is used to match to a infinite introduced in the sequence. This infinite is normally called a spread. The spread is viewed as interpolation in one sequence and omission in the other. A mark is used to mensurate the alliance public presentation. The highest mark one is the best alliance. For lucidity ‘s interest, the generic MSA job is expressed with the following declaration: â€Å" Insert spreads within a given set of sequences in order to maximise a similarity standard † [ 24 ] . The MSA job can be divided into three troubles, which are scalability, optimisation, and nonsubjective map. Finding an accurate MSA from sequences is really hard. It is a clip consuming and computationally NP-hard job [ 13-15 ] . In fact, that complexness comes from that all three jobs must be solved at the same time. The first job is the scalability, which is to happen the alliance of many long sequences. The 2nd job is the optimisation, which is to happen the alliance with the highest mark based on a given nonsubjective map among sequences. Optimization of even a simple nonsubjective map is an NP-hard job. The 3rd job is the nonsubjective map ( OF ) , which is to rush up the computation in order to mensurate the alliance. Most modern plans for building multiple sequence alliances ( MSAs ) consist of two constituents: an nonsubjective map for measuring the quality of a candidate alliance of a set of input sequences, and an optimisation process for placing the highest scoring alliance with regard to the chosen nonsubjective map [ 25 ] .3.0 Objective mapsAligning multiple sequences is a extremely non-trivial undertaking ( in both a biological and computational sense ) whose truth in pattern depends mostly on the pick of input sequences, the cost ( or aim ) map, and the heuristics employed [ 26 ] . An of import facet of alliance mark is to set up how meaningful a given multiple alliance is. This is to find whether the aligned sequences are in fact optimum and to gauge the mark of the alliance in which there is no anterior cognition of the mention alliance. Objective map is the psyche of iterative algorithms in the sense that it determines the campaigner move to be taken to better the solution quality. In multiple sequence alliance, nonsubjective map Acts of the Apostless as the cardinal factor to command the development of an alliance into a mature one. Using optimisation algorithm to work out any job requires delegating a fittingness map. In harmony hunt algorithm, this map evaluates and ranks harmoniousnesss in the harmoniousness memory harmonizing to their tonss. Harmonies that ain good alliance mark in the harmoniousness memory are retained. In this subdivision different nonsubjective maps are studied. The pick of nonsubjective map is strictly a biological job that lies in the definition of rightness. A mathematical map able to mensurate an alignment biological quality that defines a right alliance and its expected belongingss is called nonsubjective map ( OF ) . Given a perfect map, the mathematically optimum alliance assumes to be biologically optimum. While the map defines a mathematical optimum, it is seldom that this optimum will besides be biologically optimum [ 25 ] . There are different nonsubjective maps to hit the quality of the alliance, viz. sum-of-pairs, leaden sum-of-pairs, and NorMD [ 23 ] , MstatX, amd COFFEE [ 22 ] . They are used in optimizing and iterative alliance methods to better the alliance by seeking to maximise the nonsubjective map [ 27 ] .3.0.1 sum-of-pairsPresently sum-of-pairs nonsubjective map is most widely used [ 28 ] . Carrillo and Lipman [ 29 ] foremost introduced the sum-of-pairs ( SP ) mark map, which defines the tonss of a multiple alliance of N sequences as the amount of the tonss of the N ( N-1 ) /2 pairwise alliances [ 29 ] , [ 30 ] . Although SP mark map has been widely used to measure MSA, it does n't truly supply any biological or probabilistic justification [ 30 ] . Each sequence is scored as if it is descended from the N-1 other sequences alternatively of a individual ascendant. As a consequence, evolutionary events are frequently overestimated. The job worsens as the figure of sequences additions [ 30 ] the sum-of-pairs ( SP ) mark described in [ 31 ] , [ 32 ] , [ 29 ] , [ 33 ] is used to cipher the nonsubjective map ( OF ) where there is no anterior cognition of the mention alliance. The general signifier of OF mark of alignment n sequences consist of m columns is OF = . Where is the similarity mark of the column myocardial infarction, is the spread punishment of the column myocardial infarction and is the sequence length. The similarity mark of the column myocardial infarction can be measured by the sum-of-pairs ( SP ) . The SP-score S ( myocardial infarction ) for the i-th column myocardial infarction is calculated as follows: S ( myocardial infarction ) = , ( ) where is the j-th row in the i-th column. For alining two residues x and y, the permutation matrix s ( x, y ) is used to gives the similarity mark.3.0.2 Weighted sum-of-pairsThe leaden sum-of-pairs ( WSP ) score [ 28 ] , [ 34 ] is an extension of SP mark so that each pairwise alliance mark otherwise contributes to the whole mark. A leaden SP mark map has been proposed in the manner to reflect the relationships between the sequences. The rule is to give a cost to each brace of aligned residues in each column of the alliance ( permutation cost ) , and another cost to the spreads ( spread cost ) . These are added to give the planetary cost of the alliance. Furthermore, each brace of sequences is given a weight related to their similarity to other braces. The WSP calculates a entire mark from the leaden pairwise mark of all the sequences. The undermentioned figure shows the mathematical preparation of the leaden SP mark map. WSP ( A ) = ( ) Where N is the figure of sequences, k the length of aligned sequences, is the weight given to a brace of sequences, and is the similarity cost of two symbol sequence ( ) . The cost map included spread gap and extension punishments for gap and widening spreads. The weight of pairwise aligned sequences may be proportionately score [ 35 ] , [ 36 ] harmonizing to the sum of alone information enclosed in the sequence. These weights try to diminish the influence of excess information from strongly related sequences. A weight represents a per centum equal to a per centum individuality ( PID ) calculated over each brace of aligned sequences [ 24 ] as follows ( excepting spreads ) : PID = ( )3.0.3 Normalized Mean Distancenormalized mean distance ( NorMD ) [ 23 ] is a normalized mean distance ( MD ) mark measures the normalized mean distance between the similarities of the residue braces at each alliance column, introduce in ClustalX, between similarities of residue braces at each alignment column. A mark for each column in the alliance is calculated utilizing the construct of uninterrupted sequence infinite introduced by [ 37 ] and the column tonss are so summed over the full length of the alliance. NorMD take into history the sequence information, such as the figure, length and similarity of the sequences to be aligned. NorMD is used in RASCAL [ 38 ] and AQUA [ 39 ] .3.0.4 Consistency markConsistency-based nonsubjective maps focus on improved marking of lucifers in early alliances by integrating information from of pairwise alliance. This consistence construct was originally introduced by Gotoh [ 40 ] and subsequently refined by Vingron and Argos [ 41 ] . Kececioglu [ 42 ] reformulated this job as a maximal weight hint ( MWT ) job. It was further expanded by Morgenstern [ 43 ] who proposed the first heuristic to work out this job for big cases. Consistency-based marking is used in T-Coffee [ 44 ] , MAFFT [ 45 ] , and Align-m [ 46 ] algorithms. The COFFEE [ 22 ] is a consistency-based which step optimized the figure of aligned residues that were besides aligned in planetary pairwise alliances of the same sequences. Coffee nonsubjective map which evaluates the consistence between a multiple sequence alliance and a antecedently defined library of pair-wise alliances. COFFEE required two constituents: ( I ) a set of pairwise mention alliance by utilizing any method for doing pairwise alliances, ( two ) the OF that evaluate the consistence between a multiple alliance and the pairwise alliances contain in the library. COFFEE plants by first bring forthing the pairwise library of the sequences in the alliance and so calculates the degree of individuality between the current multiple alliance and the pairwise library. COFFEE is non using excess spread punishments so that, it is non sensitive to the permutation tonss of amino acids, the mark is normalized, and the cost of similar braces is place dependent. Coffee is reflect the deg ree of consistence between a multiple sequence alliance and a library containing pairwise alliances of the same sequences. The planetary mark mensurating the quality of the alliance is computed by the undermentioned expression. Coffee mark = ( ) where Len is the length of the MSA ; Aij is the pairwise projection of sequences Si and Sj obtained from the MSA ; Wij is the per centum individuality between the two aligned sequences Si and Sj ; is the figure of residues braces that are shared between Aij and the pairwise. In add-on, utilizing chance in consistence leads to a alleged chance consistency. This hiting map is introduced in ProbCons [ 47 ] . It assigns position-specific permutation tonss based on a step of expected truth derived from a concealed Markov theoretical account. This thought is implemented and extended in the PECAN [ 48 ] , MUMMALS [ 49 ] , PROMALS [ 50 ] , ProbAlign [ 51 ] , ProDA [ 52 ] , and PicXAA [ 53 ] plans.3.0.5 POsition-Specific and consIstency-based nonsubjective function ( POSITION )POSITION [ 54, 55 ] is based on the consistence, it calculates the degree of individuality between the current multiple alliance and the pairwise library. The hiting map for POSITION is shown as under in Eq. ( 5 ) . POSITION = ( 5 ) where N is the figure of the sequences ; Aijl is the brace of residues at index cubic decimeter of the pairwise projection of sequences Si and Sj ; and Occurrence ( Aijl ) is a 0-1 binomial map of whether brace Aijl occurs in the pairwise library. W ( Aijl ) is the weight of Aijl and is assigned to the mean similarity of residue braces around index l. This is an attempt to specify the weight harmonizing to contextual information of residue braces.3.0.6 MaxZMaxZ is a statistical alliance quality mark introduced in [ 56 ] which first quantifies the grade of preservation at each alignment place and so counts the figure of significantly conserved places over the alliance. It used Zscore for mensurating the grade of preservation that is based on profile analysis [ 57 ] Then, by utilizing the importance trying method [ Using the SIR algorithm to imitate posterior distributions. ] , the statistical significance of an observed mark value is calculated. In footings of positional significance degrees, the full alliance mark is calculated.3.0.7 MstatXMstatX calculates the trident statistic of each column in the multiple sequences alliance. Then by stipulate the statistic with the flag options. It can gives many different statistical steps on columns of a multiple alliance like Shannon information, frequence counts, spread counts, and more sophisticated marking. The default statistic is a weighted-entropy which means a Shannon information based on chances computed with the sequence burdening strategy defined by [ 58 ] . Statisticss proposed in MstatX is based on [ 59 ] and [ 60 ] .3.0.8 Maximal expected truth ( MEA )Maximal expected truth ( MEA ) [ 61 ] : The basic thought of MEA is to maximise the expected figure of â€Å" right † aligned residue braces [ 62 ] . It has been used in PRIME [ 63 ] , and ProbCons [ 47 ] algorithms.3.0.9 Segment-to-segment nonsubjective mapSegment-to-segment nonsubjective map: It is used by DIALIGN [ 64 ] to build an alliance through comparing of the whole sections of the sequences instead than the residue-to-residue comparing.3.0.10 Profile markProfile hiting map uses a marking map which is defined for a brace of profile places. In add-on to SP, MUSCLE [ 65 ] uses a new profile map which is called the log-expectation ( LE ) mark. Some of these nonsubjective maps integrated into other nonsubjective maps, each have its ain advantages and disadvantages. The nonsubjective map presently used in DIALIGN that is segment-to-segment nonsubjective map is flawed [ 66 ] . On the other manus T-Coffee is excessively memory demanding [ 12 ] . Sum-of-pairs is the most popular marking method because of its comparative velocity and hardiness. The velocity advantage is chiefly because the sum-of-pairs method does non necessitate a tree [ 67 ] . Some nonsubjective maps use permutations matrices whereas other used consistence construct by involve pairwise alliance. [ 68 ] disadvantage of these permutations matrices is that they are intended to rate the similarity between two sequences at a clip merely, and in order to widen them to multiple sequences, it is common to happen that they are scaled by adding up each pairwise similarity to obtain the mark for the multiple sequence alliance [ 5 ] .4.0 Alignment QualityQ ( Quality ) is a quality map to gauge the comparing between the alliance and the mention alliance. Q mark is the figure of right aligned residue braces in the trial alliance divided by the figure of residue braces in the mention alliance. This has been termed as the developer mark [ 69 ] and SPS [ 31 ] .5.0 MATERIALS AND METHODSHarmony hunt algorithm – which is out of range of this paper – is used to happen the optimal or a close optimum alliance harmonizing to the nonsubjective map. Given a perfect map, the mathematically optimum alliance will besides be biologically optimum. While the map defines a mathematical optimum, it is seldom have an statement that this optimum will besides be biologically optimum. two type of dataset are chosen ( I ) the subset of BRAliBase which are extremely variable and suited for local MSA ; ( two ) LocalEXtR, an extension of BRAliBase 2.1, consisting large-scale trial groups and patterned on BRAliBase 2.1 ; The series of experiments has been conducted in order to analyze the relationship of the corresponding nonsubjective map mark with the alignment quality. The experiment has been done in the term of correlativity coefficient between the nonsubjective map mark and the alignment quality mark in one side and the consuming clip in another side. First, the different nonsubjective maps are used as a fittingness map in HS algorithm and the relationship between them are studied. Second compare the quality tonss of 5 nonsubjective map utilizing database In pattern, it is hence ever recommended to utilize as many different methods. hence analysis did non curtail to merely a few of the best alignment methods but aimed to utilize as many methods as possible [ 12 ] . One of the primary challenges in sequence alliance is to happen a biologically meaningful nonsubjective map. A common pick of many alliance algorithms has been the ‘sum-of-pairs ‘ ( SP ) mark, which merely takes the amount of the tonss of all pairwise alliances in a given multiple alliance. To day of the month, there is no nonsubjective map that has been every bit good accepted for multiple alliances [ 70 ] as similarity has been for pairwise alliance. Alignment quality requires a mention alliance from database benchmark. The comparing is between the trial alliance and the mention alliance and it is called here alignment quality.Performance ratingTwo scenarios are done in different manner, The first scenarios, it uses an nonsubjective map in the HS Improvising procedure and analyze the relationship between the alliance mark with alignment quality for concluding alliance. This is repeated with all nonsubjective map. The motive for mark the alliance many times in every loop was the fact that alliances generated prior to the several iterative polish are frequently rather different from the concluding alliance [ 12 ] . Second scenarios, it measures alignment mark and alignment quality for the same alliance which is the concluding alliance by every nonsubjective maps individually. Alignment mark and its quality are compared for each alliance. This seneraio is to compare the consequence of different nonsubjective map on the same alliance These experiments to cognize how strong is the relation between them in each nonsubjective map individually. A comprehensive reappraisal of all methods will non be given here, but the common nonsubjective maps will be focus on.a. Harmony hunt algorithmHarmony hunt algorithm ( HS ) is developed by Geem [ 21 ] . HS is a meta-heuristic optimisation algorithm based on music. HS is imitating a squad of instrumentalists together seeking to seek the best province of harmoniousness. Each participant generates a sound based on one of three options ( memory consideration, pitch accommodation, and random choice ) . This is tantamount to happen the optimum solution in optimisation procedure. Geem et Al. [ 21 ] theoretical accounts HS constituents into three quantitative optimisation procedure as follows: first procedure, the Harmony memory ( HM ) : It used to maintain good harmoniousnesss. A harmoniousness from HM is selected indiscriminately based on the parametric quantity called harmony memory sing ( or accepting ) rate, HMCR ?„ [ 0,1 ] . It typically uses HMCR = 0.7 ~ 0.95. Second procedure, the pitch accommodation: it is similar to local hunt. It is used to bring forth a somewhat different solution from the HM depend on pitch-adjusting rate ( PAR ) values. PAR control the grade of the accommodation by the pitch bandwidth ( brange ) . It normally uses PAR = 0.1~0.5 in most applications. Third procedure, the random choice: a new harmoniousness is generated indiscriminately to increase the diverseness of the solutions. The chance of randomisation is Prandom = 1- HMCR, and the existent chance of the pitch accommodation is Ppitch = HMCR A- PAR. The pseudo codification of the basic HS algorithm with these three constituents is summarized in Figure 1. Harmony Search Algorithm Get down Declare the nonsubjective map degree Fahrenheit ( x ) , ten = ( x1, x2, aˆÂ ¦ , xn ) Initialize the harmoniousness memory accepting rate ( HMCR ) Initialize pitch seting rate ( PAR ) and other parametric quantities Initialize Harmony Memory with random harmoniousnesss While ( t & lt ; max figure of loops ) If ( rand & lt ; HMCR ) , Choose a value from HM If ( rand & lt ; PAR ) , Adjust the value by adding certain sum End if Else Choose a new random value End if End while Measure the solution by utilizing nonsubjective map Accept the new harmoniousness ( solution ) if better Update HM End while Find the current best solution in HM End Figure 1 Pseudo Code of the Harmony Search Algorithm [ 71 ] The HS algorithm has been applied to assorted optimisation jobs [ 72 ] that include Real-world applications, Computer scientific discipline jobs, Electrical technology jobs, Civil technology jobs, Mechanical technology jobs, and Bio & A ; medical applications.B. Benchmark DatasetThree type of dataset are chosen ( I ) the subset of BRAliBase which are extremely variable and suited for local MSA ; ( two ) LocalEXtR, an extension of BRAliBase 2.1, consisting large-scale trial groups and patterned on BRAliBase 2.1 ; ( three ) Lset, a brace of large-scale trial sets representative of current biological job. The subset of the BRAliBase 2.1 are selected from the most variable dataset within the suite. They are from THI, Glycine riboswitch and Yybp-Tkoy RNA households, and contain 232 trial datasets. LocalExtR uses the same seed alliances from Rfam that BRAliBase uses and signifiers big trial groups. BRAliBase is label a trial group qi, where I is the figure of sequences for each trial set in the group. The tabular array ( 1 ) and ( 2 ) show the inside informations of the dataset and the description information about each trial set. Table 1: Trial Dataset Number of each Test Group trial Group gcvT Family THI Family yybp-ykoy Family BRALiBase 2.1 ( 232 datasets ) k5 22 69 33 k7 12 32 18 k10 3 17 12 k15 1 5 8 LocalExtR ( 90 datasets ) k20 10 10 10 k40 10 10 5 k60 10 10 0 k80 5 10 0 Entire 73 163 86 Table 2: Sequence length of each Test Group sequence length trial Group Avg. Min. BRALiBase 2.1 ( 232 datasets ) k5 109 96 k7 110 94 k10 108 94 k15 110 88 LocalExtR ( 90 datasets ) k20 115 90 k40 114 87 k60 107 81 k80 106 775.0 RESULTS AND DISCUSSIONOne chief challenge with MSA is how to gauge the quality of computer-aligned sequences. Therefore, an nonsubjective map ( OF ) is required in the optimisation processes. The pick of nonsubjective map and heuristics is critically of import in obtaining high quality alliances [ 12 ] . In add-on, OF acts an indispensable function in optimisation algorithms whereby the alliance is optimized against a mark computed by the OF [ 2 ] . The most straightforward OF is the sum-of-pairs ( SP ) score [ 3 ] , weight sum-of-pair [ ] , java [ 22 ] , Xstate [ ] and NorMD [ 23 ] .5.1 Correlation between Objective maps Score and alignment qualityTheoretically, an OF should ever give higher tonss for alliance with better quality [ ] . In world, nevertheless, since the nonsubjective map tonss and the alliance qualities are measured utilizing different standards, incompatibility happens. Correlation between alignment quality and different nonsubjective maps score were practiced on each experimental. Correlation coefficients ( R2 ) were so computed for each nonsubjective map and Q mark of the alignment quality. Two scenarios are performed to look into the correlativity the first one where utilizing the nonsubjective map as the HS Improvising procedure, the 2nd one where mark a concluding alliance by different nonsubjective maps. ( a ) First Scenario: utilizing the nonsubjective map in the generator procedure Five experiments are carried by utilizing an nonsubjective map and compared alignment mark with alignment quality in each experiment. Each experiment has been repeated 5 times for the same dataset and the norm is calculated. In this experiment, each nonsubjective map have been used individually as a fittingness map. Then, the correlativity of the nonsubjective map mark and the alignment quality mark is calculate utilizing the Correlation coefficients ( R2 ) . Each instance has been repeated 5 tallies for same dataset and calculated the norm for each nonsubjective map theoretical accounts. The figure of loop in each tally, is fixed in all the experimental in this experiment to 10,000. 322 trials set are used and their inside informations are summarized in Mistake: Reference beginning non found HS parametric quantities and others parametric quantities are setup to default puting for all nonsubjective map. Alliance Generator OF1 Alliance Mark |qualityaˆÂ ¦Alliance Generator OF2 Alliance Mark |qualityaˆÂ ¦In this experimental BHS-MSA is used to bring forth the alliance. Within the optimisation processes the nonsubjective map theoretical accounts, sum-of-pairs, weight sum-of-pair, java, Xstate and NorMD were used individually to give the good alliance quality. The concluding alliances were measured and evaluated by comparing with the mentions utilizing the rating map Quality ( Q ) and Entire column Score ( TC ) . The mean correlativity coefficient value of all dataset is listed and the spread secret plan graphs are listed as shown in Figure 2. shows the R indicated that the java and sum-of-pairs nonsubjective map has better positive correlativity with alignment quality than others does. The relation is positive that mean when the nonsubjective map is increase the alignment quality is increase this is clear shows in the Figure 3. Table 3: Correlation coefficients ( R2 ) of option Objective maps for scenario 1 SP WSP NorMD MstatX Coffee Correlation coefficients ( R2 ) 0.9216 0.7278 0.7613 0.8259 0.9642 fig 2 copy.jpg Figure 2: Scatter secret plan of alternate nonsubjective Functions for scenario 1 ( B ) Second Scenario: step a concluding alliance by different nonsubjective maps. In this experimental, 10 experiments are transporting out and alliance are bring forthing indiscriminately. Final alliance is measured by each nonsubjective map individually. Then, the correlativity of the nonsubjective map mark and the alignment quality mark is calculate utilizing the Correlation coefficients ( R2 ) [ 12 ] . This scenario is to back up the old 1. The correlativity on different nonsubjective map on alliances is study here by another manner where the nonsubjective maps are step the same alliance together and the relationship between the alliance mark with alignment quality are studied individually for each nonsubjective map. For ocular review, matching spread secret plans for all nonsubjective maps are presented. Alliance Generator OF1 Alliance Mark |qualityaˆÂ ¦aˆÂ ¦aˆÂ ¦OF2 Mark |qualityaˆÂ ¦aˆÂ ¦aˆÂ ¦HS and MSA parametric quantity are fixed to same values in all experimental. The mean correlativity coefficient value of all dataset is listed in Table 4 and the spread secret plan graphs are shown in Figure aˆZ3 Table4 shows the R indicated that the java and sum-of-pairs nonsubjective map has better positive correlativity with alignment quality than others does. The relation is positive that mean when the nonsubjective map is increase the alignment quality is increase this is clear shows in the Figure aˆZ3 Table 4: Correlation coefficients ( R2 ) of option Objective maps for scenario two sum-of-pairs ( R ) wsop ( R ) NorMD ( R ) Xstat ( R ) Coffee ( R ) Correlation coefficients ( R2 ) 0.8319 0.7558 0.6762 0.8028 0.9494 fig 3 copy.jpg Figure aˆZ3: Scatter secret plans of alternate nonsubjective maps for scenario two5.2 Study of Coffee and SP Objective maps based on clip costObjective map is the most computationally time-consuming constituent of MSA alliance method. The clip complexness of calculating an nonsubjective mark additions linearly with length of alliance and the figure of sequences. Figure aˆZ shows that increasing the sequence figure lead to increase the clip cost for calculate the nonsubjective map for the java and SP nonsubjective maps. Table5: Time cost of each Test Group Test Group No. of Seqs. sequence length Avg. Time Avg. min soap SP BRALiBase 2.1 ( 232 datasets ) k5 5 109 96 125 0.16 k7 7 110 94 131 0.32 k10 10 108 94 129 0.66 k15 15 110 88 137 1.60 LocalExtR ( 90 datasets ) k20 20 115 90 172 3.52 k40 40 114 87 180 16.96 k60 60 107 81 189 42.72 k80 80 106 77 204 88.01 Based on the correlativity shown in 4, the correlativity between the alliances hiting and the alignment quality utilizing the COFFEE nonsubjective map and sum-of-pairs were better than those found utilizing the NorMd, MstatX, and WSP nonsubjective maps. Coffee and sum-of-pairs nonsubjective maps have the highest correlativity. Based on the clip cost shown in Table5: Time cost of each Test Group and figure 4, the cost clip used by sum-of-pairs is better than java nonsubjective map for all trial groups. Figure aˆZ4: Coffee and SPS Objective map clip6.0 DecisionThe alliance of multiple sequences remains a challenging job today. Here, we do non discourse possible schemes to better alliance quality, but alternatively concentrate on the maps used to measure the quality of completed alliances. The relationship of the alliance mark and alignment quality of different nonsubjective map is the aim of this paper. It is recommended to run several maps and compare their consequences to happen the most suitable one. The consequence shows that the correlativity between the alliances tonss and the alignment quality utilizing the COFFEE nonsubjective map and sum-of-pairs were better than those found utilizing the NorMd, MstatX, and WSP nonsubjective maps. Coffee and sum-of-pairs nonsubjective maps have the highest correlativity. It besides shows that the alliance marking by sum-of-pairs is better than java nonsubjective map for all trial groups in footings of consuming clip The tonss produced by sum-of-pairs and java are better correlated to the existent alliance truths than tonss produced by other methods.7.0 RecognitionThe writers would wish to appreciate the School of Computer Sciences every bit good as University Science Malaysia for their installations and aid. The writers are appreciative of the attempts of the referees for their helpful remarks.